
1. It's About Regeneration, Not Just Filling
When considering aesthetic treatments, many people are familiar with dermal fillers that work by adding volume to smooth out lines and wrinkles instantly. rejuran operates on a fundamentally different principle. Instead of merely acting as a temporary filler, its core ingredient—polynucleotides (PN)—engages with your skin's biology at a cellular level. Think of polynucleotides as building blocks or essential nutrients derived from purified salmon DNA. When injected into the skin, they don't just sit there; they actively communicate with your cells, signaling them to kickstart the body's own natural healing and regeneration processes.
This mechanism is what sets Rejuran apart. It works by stimulating fibroblasts, which are the cells responsible for producing collagen, elastin, and hyaluronic acid. Over time, this leads to a genuine improvement in your skin's foundational structure. You're not just masking a problem; you're encouraging your skin to repair and rebuild itself from within. The benefits, therefore, extend beyond a single line. Patients often notice a comprehensive enhancement in skin texture, with a reduction in fine lines, improved elasticity, and a healthier, more radiant overall complexion. The goal of Rejuran is long-term skin health, offering results that look and feel like a naturally better version of you, rather than an obvious "treatment" look.
2. A Course of Treatments is Standard
It's important to manage expectations from the outset. Unlike some cosmetic procedures that deliver dramatic changes in a single visit, Rejuran is designed as a regenerative treatment course. A single session is considered a starting point, not a complete solution. Most qualified practitioners will recommend an initial series of 3 to 4 treatment sessions. These are typically spaced about 2 to 4 weeks apart. This structured approach is not arbitrary; it's scientifically aligned with how skin regeneration works.
Each session builds upon the last, creating a cumulative effect. The first treatment begins the process of cellular signaling and laying the groundwork. The subsequent sessions reinforce this signal and provide a sustained supply of polynucleotides, ensuring that the regenerative process continues robustly over several weeks. This multi-session protocol is crucial for achieving optimal and lasting results. It allows for progressive improvement in skin density, hydration, and firmness. After completing the initial course, many individuals opt for maintenance treatments, perhaps once or twice a year, to help sustain the rejuvenated effects. Viewing Rejuran as an investment in a treatment plan, rather than a one-off procedure, is key to being satisfied with the long-term outcome.
3. Results are Gradual and Natural-Looking
If you're seeking an instant, "over-night" transformation, Rejuran may not align with that expectation—and that's actually one of its greatest strengths. The beauty of this treatment lies in its subtlety and the natural progression of results. Immediately after the injections, you might see some initial hydration and mild plumping, but the true magic happens invisibly beneath the surface in the weeks that follow. As the polynucleotides stimulate your fibroblasts, your skin gradually begins to produce new, high-quality collagen and elastin fibers.
This biological process takes time. Patients typically start to notice visible changes around 4 to 6 weeks after their first treatment, with the most significant improvements becoming apparent 1 to 2 months after completing the full course. The changes are incremental: skin texture becomes smoother, pores appear refined, fine lines soften, and overall firmness and luminosity improve. Because you are enhancing your own skin's biology, the result is a refreshed, revitalized, and healthier appearance. There is no drastic alteration of your facial features. Friends and family might simply comment that you look well-rested or glowing, without being able to pinpoint a specific "done" procedure. This natural-looking outcome is a core reason why Rejuran has gained such popularity among those who prefer a discreet yet effective approach to anti-aging.
4. It's Versatile for Face and Body
While facial rejuvenation—addressing concerns like nasolabial folds, perioral lines, and overall skin laxity—is the most common application for Rejuran, its utility is remarkably broad. The principle of stimulating skin regeneration is not limited to the face. Practitioners are successfully using Rejuran injections to improve skin quality on various parts of the body that show signs of aging, sun damage, or texture issues.
Common treatment areas beyond the face include the neck and décolletage (chest), where thin, crepey skin and horizontal lines can be a concern. The backs of the hands are another prime area, as they often reveal age through thinning skin, prominent veins, and sun spots. Rejuran can help improve the thickness, elasticity, and overall texture of the skin in these regions, making them appear smoother and more youthful. It can also be used to enhance skin healing and quality in areas with minor scars or stretch marks. This versatility makes Rejuran a comprehensive tool for holistic skin rejuvenation, allowing individuals to address concerns on multiple fronts with a single, scientifically-backed product that promotes the skin's innate ability to heal and restore itself.
5. Post-Treatment Care is Simple but Crucial
One of the appealing aspects of Rejuran is its minimal downtime. However, to protect your investment and ensure the best possible regenerative results, adhering to simple aftercare guidelines is essential. Immediately following your treatment, you may experience mild redness, swelling, or tiny bumps at the injection sites. These are normal and usually subside within a few hours to a couple of days.
For the first 24 to 48 hours, it is vital to avoid exposing the treated area to intense heat. This means steering clear of saunas, steam rooms, hot yoga, and prolonged hot showers. You should also avoid strenuous exercise that causes excessive sweating during this initial period. Gentle cleansing with a mild, non-abrasive cleanser is recommended. Perhaps the most critical component of aftercare—and ongoing skin health—is rigorous sun protection. UV radiation is a primary driver of skin aging and can undermine the regenerative work Rejuran is doing. Applying a broad-spectrum sunscreen with high SPF daily, and reapplying as needed, is non-negotiable. Keeping the skin well-hydrated with a gentle moisturizer will also support the healing environment. By following these straightforward steps, you create the ideal conditions for your skin to respond optimally to the treatment, leading to more effective and longer-lasting results from your Rejuran regimen.

